Characteristics | Altis (n = 63) | Solyx (n = 50) | Abbrevo (n = 119) | p-value for all | Data available Altis/Solyx/Abbrevo |
Demographic | |||||
Age, y, mean ± SD | 55.3 ± 11.6 | 52.2 ± 11.7 | 50.8 ± 9.9 | 0.032 | 63/50/118 |
Parity total [median (IQR)]a | 2 (2,3) | 2 (2,3) | 3 (2,3) | 0.032 | 61/49/99 |
Parity vaginal [median (IQR)] | 2 (2,3) | 2 (1,3) | 3 (2,3) | 0.004 | 61/49/99 |
BMI, mean ± SD | 26.2 ± 5.3 | 26.0 ± 4.1 | 26.1 ± 5.1 | 0.98 | 56/44/95 |
Post menopausal status, n (%) | 35 (55.6) | 21 (45.7) | 28 (28.0) | 0.001 | 63/46/100 |
Previous Hysterectomy, n (%) | 9 (14.3) | 5 (10.9) | 15 (16.7) | 0.661 | 63/46/90 |
Previous POP surgery, n (%) | 3 (4.8) | 4 (8.7) | 13 (12.5) | 0.247 | 63/46/104 |
Previous SUI surgery, n (%) (Burch colposuspension n = 5) | 5 (7.9) | 0 (0) | 3 (2.9) | 0.087 | 63/46/103 |
Total PMHx, n (%)b | 17 (27.0) | 9 (19.6) | 16 (14.8) | 0.151 | 63/46/108 |
Baseline Functional Outcomes | |||||
PGI-S [median (IQR)]a | 3 (3,4) | 3 (3,4) | 3 (2,3) | <0.001 | 56/42/105 |
Antimuscarinic use, n (%) | 5 (8.3) | 7 (14.6) | 7 (7.4) | 0.357 | 60/48/95 |
Urodynamic findings | |||||
Detrusor overactivity, n (%) | 7 (11.5) | 2 (4.1) | 7 (6.6) | 0.407 | 61/49/106 |
MUCP (cm H20), mean ± SD | 45.7 ± 18.0 | 43.5 ± 19.4 | 42.2 ± 16.3 | 0.492 | 55/47/98 |
ALPP (cm H20), mean ± SD | 121.1 ± 31.9 | 119.1 ± 34.4 | 115.3 ± 46.4 | 0.697 | 48/46/91 |
Maximum flow rate (ml/sec), mean ± SD | 31.9 ± 14.2 | 30.7 ± 12.5 | 26.4 ± 10.8 | 0.014 | 61/49/101 |
Post void residual volume (ml), mean ± SD | 22.4 ± 25.3 | 24.4 ± 26.3 | 27.8 ± 28.2 | 0.448 | 61/49/104 |
POP-Q staging [median (IQR)]a | |||||
Ba | −1 (−2, 0) | −1 (−2, 0) | −1 (−2, 0) | 0.132 | 51/47/101 |
Bp | 0 (−2, 0) | −2 (−3, 0) | −1 (−2, 0) | 0.056 | 51/48/98 |
C | −5 (−6, −4) | −6 (−7, −5) | −6 (−7, −4.75) | 0.043 | 52/46/99 |
Prolapse surgery | |||||
Concomitant POP, n (%) | 34 (54.0) | 26 (55.3) | 61 (51.3) | 0.875 | 63/47/119 |
VH ± A/P or AP, n (%) | 27 (42.9) | 23 (50.0) | 49 (41.2) | 0.588 | 63/46/119 |
Anterior/apical mesh, n (%) (Uphold® TVM or ASC) | 2 (3.2) | 1 (2.2) | 2 (1.7) | 0.838 | 63/46/119 |
Posterior Repair, n (%) (no posterior mesh) | 5 (7.9) | 2 (4.3) | 10 (8.4) | 0.75 | 63/46/119 |
Maximum flow rate: post void residual assessment performed at uroflowmetry prior to consent for continence surgery.
PGI-S:patient global impression of severity; MUCP: maximum urethral closure pressure; ALPP: abdominal leak point pressure; VH ± A/P or AP: vaginal hysterectomy, vault suspension, anterior ± posterior repair; TVM: transvaginal mesh; ASC: abdominal sacrocolpopexy; POP: Pelvic Organ Prolapse; PMHx: Past Medical History; SUI: stress urinary incontinence, n: number of cases.
↵a Median (interquartile range Q1,Q3).
↵b Medical history of diabetes milletus, cardiovascular, respiratory, neurological, connective tissue disorders.