Inflammatory cytokines | Trend | Main function | Reference |
IL-1β | ↑ | Involved in the inflammatory response | Amjadi et al., 2022 |
IL-2 | ↑ | Involved in the inflammatory response | Liu et al., 2022 |
IL-6 | ↑ | Involved in the inflammatory response | Liu et al., 2022 |
Induced cytokine production and recruitment of macrophages and megakaryocytes | Piltonen et al., 2013 | ||
Inhibited insulin signaling | Oróstica et al., 2020 | ||
IL-8 | ↑ | Promoted a proinflammatory response and lineage cell differentiation | Piltonen et al., 2013 |
IL-11 | ↑ | Involved in the inflammatory response | Amjadi et al., 2022 |
IL-15 | ↑ | Involved in the inflammatory response | Liu et al., 2022; Amjadi et al., 2022 |
↓ | Impaired uNK cells recruitment | Matteo et al., 2010 | |
IL-18 | ↑ | Involved in the inflammatory response | Long et al., 2017 |
↓ | Impaired uNK cells recruitment | Matteo et al., 2010 | |
CCL2 | ↑ | Induced migration of macrophages | Piltonen et al., 2013 |
CXCL10 | ↓ | Impaired uNK cells recruitment | Matteo et al., 2010 |
TNF-α | ↑ | Involved in the inflammatory response | Hu et al., 2021; Amjadi et al., 2022 |
IFN-α | ↑ | Involved in the inflammatory response | Hu et al., 2021 |
IFN-γ | ↑ | Involved in the inflammatory response | Hu et al., 2021 |
TGF-β | ↑ | Involved in the inflammatory response | Amjadi et al., 2022 |
↑ up-regulation; ↓ down-regulation.
IL, interleukin; CCL2, C–C motif chemokine ligand 2; CXCL10, chemokine ligand 10; TNF-α, tumor necrosis factor α; IFN, interferon γ; TGF-β, transforming growth factor-β; uNK, uterine natural killer. ↑ up-regulation; ↓ down-regulation.