Characteristic | Cohort before PSM | Cohort after PSM | ||||
BRCA wild type (n = 130) | BRCA mutant type (n = 45) | P Value | BRCA wild type (n = 420) | BRCA mutant type (n = 90) | P Value | |
Age≥65y | 0.064 | 0.894 | ||||
No | 63 (48.8) | 28 (65.1) | 21 (63.6) | 28 (65.1) | ||
Yes | 66 (51.2) | 15 (34.9) | 12 (36.4) | 15 (34.9) | ||
BMI≥28 kg/m2 | 0.005 | 0.897 | ||||
No | 32 (26.2) | 20 (50.0) | 16 (48.5) | 20 (50.0) | ||
Yes | 90 (73.8) | 20 (50.0) | 17 (51.5) | 20 (50.0) | ||
Diabetes history | 0.174 | 0.456 | ||||
No | 60 (65.9) | 23 (79.3) | 22 (71.0) | 23 (79.3) | ||
Yes | 31 (34.1) | 6 (20.7) | 9 (29.0) | 6 (20.7) | ||
Hypertension history | 0.007 | 0.945 | ||||
No | 31 (31.6) | 21 (56.8) | 19 (57.6) | 21 (56.8) | ||
Yes | 67 (68.4) | 16 (43.2) | 14 (42.4) | 16 (43.2) | ||
AJCC stage | 0.538 | 0.564 | ||||
Early (stage I-II) | 92 (70.8) | 34 (75.6) | 23 (69.7) | 34 (75.6) | ||
Advanced (stage III-IV) | 38 (29.2) | 11 (24.4) | 10 (30.3) | 11 (24.4) | ||
Lymph node metastasis | 0.733 | 0.406 | ||||
No | 95 (80.5) | 34 (82.9) | 24 (75.0) | 34 (82.9) | ||
Yes | 23 (19.5) | 7 (17.1) | 8 (25.0) | 7 (17.1) | ||
Depth of myometrial invasion | 0.238 | 0.344 | ||||
<50% | 53 (51.0) | 16 (40.0) | 13 (52.0) | 16 (40.0) | ||
≥50% | 51 (49.0) | 24 (60.0) | 12 (48.0) | 24 (60.0) | ||
Peritoneal cytology | 0.506b | 0.626b | ||||
Negative | 78 (88.6) | 33 (94.3) | 19 (90.5) | 33 (94.3) | ||
Positive | 10 (11.4) | 2 (5.7) | 2 (9.5) | 2 (5.7) | ||
Residual disease | 0.614 | 0.872 | ||||
No | 78 (76.5) | 29 (80.6) | 23 (82.1) | 29 (80.6) | ||
Yes | 24 (23.5) | 7 (19.4) | 5 (17.9) | 7 (19.4) | ||
Radiation therapy use | 0.695 | 0.927 | ||||
No | 59 (50.0) | 20 (46.5) | 15 (45.5) | 20 (46.5) | ||
Yes | 59 (50.0) | 23 (53.5) | 18 (54.5) | 23 (53.5) | ||
Chemotherapy use | 0.749 | 0.384 | ||||
No | 47 (68.1) | 20 (71.4) | 10 (58.8) | 20 (71.4) | ||
Yes | 22 (31.9) | 8 (28.6) | 7 (41.2) | 8 (28.6) | ||
Molecular targeted therapy use | 0.811 | 0.523 | ||||
No | 45 (60.8) | 19 (63.3) | 12 (54.5) | 19 (63.3) | ||
Yes | 29 (39.2) | 11 (36.7) | 10 (45.5) | 11 (36.7) |